Saturday, January 31, 2015

Check and test if you suspect...diabetic nephropathy!

Generally, patients with either type 1 and 2 diabetes should be screen yearly for any complications. 


What you would check if you suspect diabetic nephropathy?
There are the following things you can do: blood tests, urinalysis, renal imaging, renal function testing, and a kidney biopsy. 
Blood test and urinalysis are commonly done on patients to check kidney function. However, since it is not sufficient enough to see the severity the kidney damage, serum creatinine and the glomerular filtration rate (GFR) is also measured in the renal function testing.

Blood test: It is a comprehensive panel that can checks if your kidneys are functioning within the normal range. 
Urinalysis: Urine samples is a good indicator of how the kidneys are filtering the body waste. If there are high levels of microalbuminia in your urine, this may indicated renal problems. Furthermore, a urinalysis is a good indicator, but it is not accurate. The urinary albumin excretion can change and 2-3 samples may be collected over a course of time. This is to avoid any false-positive results that may be caused by something else beside kidney disease. 
Renal imaging: Magnetic resonance imaging (MRI) or ultrasound imaging may be used to see how well the blood is perfusing in the kidneys. X-ray may also be used to see if the kidneys look abnormal. 
Renal function testing: The kidney's filtering function are determined using renal analysis testing. The glomerular filtration rate calculated, which is a accurate measure of how well the kidneys/renal system is functioning. 
**Remember the glomerular is the filtration function unit of the kidneys that help the body filter the blood and excretes the waste through urine. **

Kidney biopsy: The doctor will perform a procedure called percutaneous kidney biopsy that uses a needle to extract pieces of the kidney tissue. This sample will undergo lab tests to check for any signs of disease or damage. 

Depending on the severity of kidney damage, a few or all of the following tests may be done. 

Citations:

Gross, J., De Azevedo, M., Silveiro, S., Canani, L., Caramori, M., & Zelmanovitz, T. (2005). Diabetic Nephropathy: Diagnosis, Prevention, And Treatment. Diabetes Care, 164-176. Retrieved February 1, 2015, from http://care.diabetesjournals.org/content/28/1/164.full

Bakris, G. (n.d.). Recognition, Pathogenesis, and Treatment of Different Stages of Nephropathy in Patients With Type 2 Diabetes Mellitus. Mayo Clinic Proceedings, 444-456.

Diabetic nephropathy. (n.d.). Retrieved February 1, 2015, from http://www.mayoclinic.org/diseases-conditions/diabetic-nephropathy/care-at-mayo-clinic/tests-diagnosis/con-20035589

Kidney biopsy. (n.d.). Retrieved February 1, 2015, from http://www.mayoclinic.org/tests-procedures/kidney-biopsy/basics/definition/prc-20018979

No comments:

Post a Comment